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Product Information:

EDP-305

EDP-305 is a novel and potent farnesoid X receptor (FXR) agonist, with no/minimal cross-reactivity to TGR5 or other nuclear receptors.

Cat. No.: EX-A5276    Purity: >98%
Chemical
Chemical structure of EDP-305


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg650In-stock
10mg900In-stock
25mg1250In-stock
50mg1750In-stock
100mg2750Inquire


CAS No.1933507-63-1
Purity>98%
FormulaC36H58N2O5S
Mol Weight630.921
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO ? 100 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Erstad DJ, et al. Molecular magnetic resonance imaging accurately measures the antifibrotic effect of EDP-305, a novel farnesoid X receptor agonist. Hepatol Commun. 2018 May 21;2(7):821-835.

[2]. Chau M, et al. Characterization of EDP-305, a Highly Potent and Selective Farnesoid X Receptor Agonist, for the Treatment of Non-alcoholic Steatohepatitis[J]. International Journal of Gastroenterology, 2019(1).

CoACoA of EDP-305
Smiles:[C@H]1(C[C@]2([H])[C@@H](CC)[C@@H](O)[C@]3([H])[C@]4([H])CC[C@H]([C@@H](CCNC(=O)NS(=O)(=O)C5=CC=C(C(C)(C)C)C=C5)C)[C@@]4(C)CC[C@]3([H])[C@@]2(C)CC1)O

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