EBV lytic cycle inducer-1

Epstein-Barr virus (EBV) lytic cycle inducer-1 Dp44mT (compound C7) is an iron-chelatoe-like compound. Dp44mT cooperates with HDAC inhibitor Romidespin and SAHA to induce EBV lytic cycle. Dp44mT reactivates EBV lytic cycle by activating the ERK1/2-autophagy axis in epithelial cancers.


Cat. No.: EX-A8095	Purity: >98%

	Chemical structure of EBV lytic cycle inducer-1

For research only, Do not use for Human!

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CAS No.	394668-43-0
Purity	>98%
Formula	C14H12BrN3O
Mol Weight	318.169
Color	White to off-white
State	solid powder
Solubility	DMSO : 12.5 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Chung King Choi, et al. Identification of Novel Small Organic Compounds with Diverse Structures for the Induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-Positive Epithelial Malignancies. PLoS One. 2015 Dec 30;10(12):e0145994. [2]. Stephanie Pei Tung Yiu, et al. Intracellular Iron Chelation by a Novel Compound, C7, Reactivates Epstein–Barr Virus (EBV) Lytic Cycle via the ERK-Autophagy Axis in EBV-Positive Epithelial Cancers Cancers 2018 Dec; 10(12): 505.
CoA	CoA of EBV lytic cycle inducer-1

Smiles:	O=C(C1=CC(Br)=CC=C1)N/N=C(C)/C2=NC=CC=C2


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