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Product Information:

EAD1

EAD1 is a potent and selective autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells.

Cat. No.: EX-A4897    Purity: 98+%
Chemical
Chemical structure of EAD1


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg875In-stock
100mg1375In-stock


SynonymsEAD1 HCl
CAS No.1644388-26-0
Purity98+%
FormulaC24H27Cl2N7
Mol Weight484.424
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Nordstrøm LU, Sironi J, Aranda E, Maisonet J, Perez-Soler R, Wu P, Schwartz EL. Discovery of autophagy inhibitors with antiproliferative activity in lung and pancreatic cancer cells. ACS Med Chem Lett. 2015 Jan 8;6(2):134-9. doi: 10.1021/ml500348p. eCollection 2015 Feb 12. PubMed PMID: 25699157; PubMed Central PMCID: PMC4329578.

[2]. Kono K, Kuzuya F, Yamamoto T, Endo H. Comparative study of cerebral ventricular dilation and cognitive function in patients with Alzheimer's disease of early versus late onset. J Geriatr Psychiatry Neurol. 1994 Jan-Mar;7(1):39-45. PubMed PMID: 8192829.
CoACoA of EAD1
Smiles:CN(CCNCC1=CN(N=N1)CC2=CC=C(C=C2)Cl)CCNC3=C4C=CC(=CC4=NC=C3)Cl

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