E3 ligase Ligand 12

cIAP1 ligand 1 is the LCL161 derivative based IAP ligand. cIAP1 ligand 1 can be connected to the ABL ligand for protein by a linker to form SNIPER. cIAP1 ligand 1 can be used in prostate cancer research[1].


Cat. No.: EX-A14667	Purity: >98%

	Chemical structure of E3 ligase Ligand 12

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	988	In-stock
1g	1780	In-stock
2g	2960	In-stock
5g	get quote	In-stock

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Synonyms	E3 ligase Ligand 12
CAS No.	2095244-42-9
Purity	>98%
Formula	C31H42N4O6S
Mol Weight	598.753
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, stored under nitrogen; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
CoA	CoA of E3 ligase Ligand 12

Smiles:	C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC(=CS3)C(=O)C4=CC(=CC=C4)O)N(C)C(=O)OC(C)(C)C


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