dWIZ1

dWIZ-1 is a potent WIZ molecular glue degrader. dWIZ-1 recruitments WIZ(ZF7) to cereblon (CRBN) induces WIZ degradation. dWIZ-1 has the potential for the research of sickle cell disease (SCD).


Cat. No.: EX-A9707	Purity: >98%

	Chemical structure of dWIZ1

For research only, Do not use for Human!

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Synonyms	dWIZ-1
CAS No.	2654005-63-5
Purity	>98%
Formula	C22H29N3O4
Mol Weight	399.4834

Reference:	[1]. Ting PY, et al. A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction. Science. 2024 Jul 5;385(6704):91-99.
CoA	CoA of dWIZ1

Smiles:	O=C1N(CC=2C1=CC=C(O[C@@H](C)[C@]3(N(CC)CCCC3)[H])C2)C4C(=O)NC(=O)CC4


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