Dual DDR1 and DDR2 inhibitor 5n

DDR1/2 inhibitor-3 (5n) is a DDR1/2 inhibitor, with IC50 valuesof 9.4 and 20.4 nM, respectively. DDR1/2 inhibitor-3 can be used in anti-inflammatory research.


Cat. No.: EX-A11285	Purity: >98%

	Chemical structure of Dual DDR1 and DDR2 inhibitor 5n

For research only, Do not use for Human!

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CAS No.	2241813-33-0
Purity	>98%
Formula	C31H31F3N6O
Mol Weight	560.6126
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Wang Z, et al. Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2- a]pyrazin-3-ylethynyl)-4-isopropyl- N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2. J Med Chem. 2018 Sep 13;61(17):7977-7990.
CoA	CoA of Dual DDR1 and DDR2 inhibitor 5n

Smiles:	O=C(NC=1C=C(C=C(C1)C(F)(F)F)CN2CCN(C)CC2)C3=CC=C(C(C#CC4=CN=C5C=NC=CN45)=C3)C(C)C


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