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Product Information:

dTRIM24

dTRIM24 is a selective bifunctional degrader of TRIM24 based on PROTAC.

Cat. No.: EX-A4448    Purity: >98%
Chemical
Chemical structure of dTRIM24


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg700In-stock
250mg1200In-stock
500mg1900In-stock
1g3300In-stock
2g4900In-stock
5gget quoteIn-stock


CAS No.2170695-14-2
Purity>98%
FormulaC55H68N8O13S2
Mol Weight1113.304
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Gechijian, Lara N et al. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands. Nature chemical biology vol. 14,4 (2018): 405-412.

CoACoA of dTRIM24
Smiles:CN(C(N1C)=O)C2=C1C=C(OC3=CC=CC(OCCC)=C3)C(NS(C4=CC(C(NCCOCCOCCOCC(N[C@H](C(N5[C@H](C(NCC6=CC=C(C7=C(C)N=CS7)C=C6)=O)C[C@@H](O)C5)=O)C(C)(C)C)=O)=O)=CC=C4)(=O)=O)=C2

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