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Product Information:

DT-061

DT-061 is an orally bioavailable activator of protein phosphatase 2A (PP2A) and could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis.

Cat. No.: EX-A5068    Purity: >98%
Chemical
Chemical structure of DT-061


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg496In-stock
50mg775In-stock
100mg1250In-stock
250mgget quoteIn-stock
500mgget quoteIn-stock
1gget quoteIn-stock


CAS No.1809427-19-7
Purity>98%
FormulaC25H23F3N2O5S
Mol Weight520.521
Color Off-white to light yellow
Statesolid powder
SolubilitySoluble in DMSO 125 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Kauko O, et al. PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Sci Transl Med. 2018 Jul 18;10(450). pii: eaaq1093.
CoACoA of DT-061
Smiles:O=S(C1=CC=C(OC(F)(F)F)C=C1)(N[C@H]2[C@H](O)[C@@H](N3C4=C(C=CC=C4)OC5=CC=CC=C35)CCC2)=O

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