DSM705

DSM705 is a pyrrole-based Dihydroorotate Dehydrogenase (DHODH) inhibitor. DSM705 exhibits nanomolar potency against Plasmodium DHODH and Plasmodium parasites, with no inhibition of mammalian DHODHs. DSM705 is a potent antimalarial compound.


Cat. No.: EX-A8449	Purity: >98%

	Chemical structure of DSM705

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	903	in_stock
10mg	1407	in_stock
25mg	2824	in_stock
50mg	4536	in_stock
100mg	7357	in_stock

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CAS No.	2653225-38-6
Purity	>98%
Formula	C19H19F3N6O
Mol Weight	404.389
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Palmer MJ, et, al. Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series. J Med Chem. 2021 May 13;64(9):6085-6136.
CoA	CoA of DSM705

Smiles:	C[C@H](C1=NC=NN1)NC(C2=C(C(C3(C4=CC=C(N=C4)C(F)(F)F)CC3)=CN2)C)=O


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