DS55980254

DS55980254 is the orally active inhibitor for phosphatidylserine synthase 1 (PTDSS1) that blocks the synthesis of intracellular phosphatidylserine. PTDSS1 deficiency affects the balance of cell membrane phospholipid components, and activates B cell receptor (BCR) signaling pathway.


Cat. No.: EX-A13913	Purity: >98%

	Chemical structure of DS55980254

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	2980	In-stock
250mg	get quote	In-stock
500mg	get quote	In-stock
1g	get quote
5g	get quote

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	2488609-43-2
Purity	>98%
Formula	C29H18F8N4O4
Mol Weight	638.4648
Color	White to off-white
State	Solid
Solubility	DMSO : 200 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, protect from light ; In solvent -20°C, 1 year.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Keisuke Suzuki, et al. Efficient Multikilogram-Scale Synthesis of PTDSS1 Inhibitor: Development of a Practical and Scalable Optical Resolution Method for Chiral 2,3-Pyrrolidinedione. Org. Process Res. Dev. 2024. [2]. Omi J, et al., Phosphatidylserine synthesis controls oncogenic B cell receptor signaling in B cell lymphoma. J Cell Biol. 2024 Feb 5;223(2):e202212074.
CoA	CoA of DS55980254

Smiles:	C(C(C)(F)F)N1[C@H](C2=C(NN=C2C1=O)C3=C4C(NC(=O)O4)=CC=C3)C5=CC=C(OC6=CC(C(F)(F)F)=CC(C(F)(F)F)=C6)C=C5


		Search