DS 7423

DS-7423 is a dual PI3K and mTOR inhibitor, with IC50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR, respectively. DS-7423 possesses anti-tumor activity.


Cat. No.: EX-A7612	Purity: >98%

	Chemical structure of DS 7423

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	385	In-stock
10mg	585	In-stock
25mg	1085	In-stock
50mg	1885	In-stock
100mg	2885	In-stock
500mg	get quote	In-stock

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Synonyms	DS-7423
CAS No.	1222104-37-1
Purity	>98%
Formula	C22H27F3N10O2
Mol Weight	520.5108
Color	White to off-white
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Katsutoshi Oda, et al. Characterization of TP53 and PI3K signaling pathways as molecular targets in gynecologic malignancies. J Obstet Gynaecol Res. 2016 Jul;42(7):757-62. [2]. Tomoko Kashiyama, et al. Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423. PLoS One. 2014 Feb 4;9(2):e87220.
CoA	CoA of DS 7423


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