DS-1206b

DS-1205b is a selective and potent AXL kinase inhibitor with IC50 of 1.3 nM. DS-1205 potently inhibited the hGAS6-induced migration in vitro with EC50 of 2.7 nM.


Cat. No.: EX-A4761	Purity: >98%

	Chemical structure of DS-1206b

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	850	In-stock
25mg	1350	In-stock
50mg	2250	In-stock
100mg	3850	In-stock
1g	get quote	In-stock
5g	get quote

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CAS No.	1855860-24-0
Purity	>98%
Formula	C41H42FN5O7
Mol Weight	735.7999
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Jimbo T, Hatanaka M, Komatsu T, et al. DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model. Oncotarget. 2019;10(50):5152–5167. Published 2019 Aug 27. doi:10.18632/oncotarget.27114
CoA	CoA of DS-1206b


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