DRP-104

Sirpiglenastat (DRP-104) is a broad acting glutamine antagonist. Sirpiglenastat has anticancer effects by directly targeting tumor metabolism and simultaneously inducing a potent antitumor immune response .


Cat. No.: EX-A10433	Purity: >98%

	Chemical structure of DRP-104

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	895	In-stock
50mg	1495	In-stock
100mg	2395	In-stock
250mg	get quote	In-stock

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Synonyms	Sirpiglenastat
Synonyms 2	DRP-104
CAS No.	2079939-05-0
Purity	>98%
Formula	C22H27N5O5
Mol Weight	441.4803
Color	Off-white to yellow
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture and light; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Yumi Yokoyama, et al. DRP-104, a novel broad acting glutamine antagonist, induces distinctive immune modulation mechanisms and synergistic efficacy in combination with immune checkpoint blockade. J Immunother Cancer. 2019 Nov 6;7(Suppl 1):282. [2]. Yumi Yokoyama, et al. DRP-104, a broad acting glutamine antagonist, synergizes with immune checkpoint blockade in vivo. Cancer Res 2021;81(13_Suppl):Abstract nr 1563.
CoA	CoA of DRP-104

Smiles:	CC(C)OC([C@H](CCC(C=[N+]=[N-])=O)NC([C@@H](NC(C)=O)CC1=CNC2=CC=CC=C12)=O)=O


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