DRL-17822

DRL-17822 is a selective cholesteryl ester transfer protein (CETP) inhibitor. DRL-17822 increases high-density lipoprotein levels. The exposure of DRL-17822 nanocrystal formulation increases significantly after a high-fat breakfast. The exposure of DRL-17822 in the fasted state is higher than that of its nanocrystal formulation. DRL-17822 can be used in the research of type II hyperlipidemia and atherosclerotic cardiovascular disease .


Cat. No.: EX-A8561	Purity: >98%

	Chemical structure of DRL-17822

For research only, Do not use for Human!

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CAS No.	898911-09-6
Purity	>98%
Formula	C30H31F6N7
Mol Weight	603.6045

Reference:	[1].Kruithof AC, et al. Effect of Food on the Pharmacokinetics of 2 Formulations of DRL-17822, a Novel Selective Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Males. Clin Pharmacol Drug Dev. 2019;8(8):1042-1052.
CoA	CoA of DRL-17822

Smiles:	FC(F)(C1=CC(CN(CC2=CC3=C(N=C2N(CC4CC4)CC5CC5)C(C)=CC=C3)C6=NN(C)N=N6)=CC(C(F)(F)F)=C1)F


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