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Product Information:

DPTIP

DPTIP is a potent brain penetrant neutral sphingomyelinase 2 (N-SMase 2) inhibitor (exosome inhibitor), with an IC50 of 30 nM.

Cat. No.: EX-A6734    Purity: >98%
Chemical
Chemical structure of DPTIP


For research only, Do not use for Human!

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CAS No.351353-48-5
Purity>98%
FormulaC21H18N2O3S
Mol Weight378.444
Color Gray to gray purple
Statesolid powder
SolubilitySoluble in DMSO 250 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Camilo Rojas, et al. DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation. Sci Rep. 2018 Dec 7;8(1):17715.

[2]. Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330.

CoACoA of DPTIP

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