DOTAGA-Glu(FAPi)-FAPi-amide

DOTAGA.Glu.(FAPi) 2 is a FAPI homodimer in which a central glutamic acid (Glu) linker connects FAPI and a chelator. Radiolabeled with gallium- 68, lutetium- 177 or terbium- 161, DOTAGA.Glu.(FAPi) 2 is applicable to FAP-positive cancer PET imaging studies. DOTAGA.Glu.(FAPi) 2 is suitable for research related to prostate adenocarcinoma and recurrent glioblastoma multiforme .


Cat. No.: EX-A15970	Purity: >98%

	Chemical structure of DOTAGA-Glu(FAPi)-FAPi-amide

For research only, Do not use for Human!

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Synonyms	DOTAGA.Glu.(FAPi)2
CAS No.	2882922-68-9
Purity	>98%
Formula	C66H81F4N15O17
Mol Weight	1432.4333
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Bilinska A, et al. Preclinical evaluation of DOTAGA.Glu.(FAPI)₂ and DO3A.Glu.(FAPI)₂ as theranostics with human dosimetry extrapolation to lutetium-177 and terbium-161 analogs. Eur J Nucl Med Mol Imaging. 2026;53(3):1887-1901. [2]. Ballal S, et al. [¹⁷⁷Lu]Lu-DOTAGA.Glu.(FAPi)₂ Radionuclide Therapy: a New Treatment Option for Patients with Glioblastoma Multiforme. Nucl Med Mol Imaging. 2024;58(1):32-34.
CoA	CoA of DOTAGA-Glu(FAPi)-FAPi-amide

Smiles:	C(NCC(=O)N1[C@H](C#N)CC(F)(F)C1)(=O)C=2C3=C(C=CC(OCCCCNC([C@@H](NC(CCC(C(O)=O)N4CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC4)=O)CCC(NCCCCOC5=CC6=C(C=C5)N=CC=C6C(NCC(=O)N7[C@H](C#N)CC(F)(F)C7)=O)=O)=O)=C3)N=CC2


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