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Product Information:

Dot1L-IN-4

Dot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor.

Cat. No.: EX-A5008    Purity: >98%
Chemical
Chemical structure of Dot1L-IN-4


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg1050In-stock
250mg1550In-stock
500mg2500In-stock
1g4200In-stock
2g6500In-stock
5g11000In-stock


Synonyms1,2-Benzenediamine, N1-[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-[4-methoxy-6-(1-piperazinyl)-1,3,5-triazin-2-yl]-4-(methylsulfonyl)-
CAS No.2565705-02-2
Purity>98%
FormulaC28H27ClF2N8O5S
Mol Weight661.079
ColorWhite to light yellow
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Stauffer F, Weiss A, Scheufler C, et al. New Potent DOT1L Inhibitors for in Vivo Evaluation in Mouse. ACS Med Chem Lett. 2019;10(12):1655-1660. Published 2019 Dec 4.
CoACoA of Dot1L-IN-4
Smiles:O=S(C1=CC=C(N[C@H](C2=NC=CC=C2Cl)C3=C4OC(F)(F)OC4=CC=C3)C(NC5=NC(OC)=NC(N6CCNCC6)=N5)=C1)(C)=O

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