Dooku1

Dooku1 is a reversibly Yoda1 antagonist with IC50 value of 1.3 μM and 1.5 μM for 2 μM Yoda1-induced Ca2+ entry HEK 293 cells and HUVECs, respectively.


Cat. No.: EX-A6810	Purity: >98%

	Chemical structure of Dooku1

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	385	In-stock
250mg	585	In-stock
500mg	865	In-stock
1g	1150	In-stock
5g	3450	In-stock
10g	get quote	In-stock

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CAS No.	2253744-54-4
Purity	>98%
Formula	C13H9Cl2N3OS
Mol Weight	326.201
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Evans EL, et al. Yoda1 analogue (Dooku1) which antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation. Br J Pharmacol. 2018 May;175(10):1744-1759. [2]. Evans EL, et al. Yoda1 analogue (Dooku1) which antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation. Br J Pharmacol. 2018 May;175(10):1744-1759.
CoA	CoA of Dooku1


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