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Product Information:

DO-264

DO-264 is a selective and in vivo-active inhibitor of Abhydrolase Domain Containing 12 (ABHD12), with an IC50 of 11 nM.

Cat. No.: EX-A3811    Purity: >98%
Chemical
Chemical structure of DO-264


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
200mg850In-stock
500mg1300In-stock
1g1950In-stock


SynonymsDO264
Synonyms 2DO 264
CAS No.2301866-59-9
Purity>98%
FormulaC23H20Cl2F3N5O2S
Mol Weight558.403
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ogasawara D, et al. Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo. Nat Chem Biol. 2018 Dec;14(12):1099-1108.

CoACoA of DO-264
Smiles:S=C(NC1=CC=CN=C1)NC2CCN(C3=NC=CC(OC4=CC=C(OC(F)(F)F)C=C4Cl)=C3Cl)CC2

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