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Product Information:

DMH2

DMH2 is a potent BMP receptor antagonist. DMH2 downregulates the expression of Id1 and Id3 proteins, and inhibits the proliferation and induces cell death of lung cancer cell lines.

Cat. No.: EX-A14277    Purity: >98%
Chemical
Chemical structure of DMH2


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg645In-stock
100mg875In-stock
500mg1715In-stock
1g2745In-stock


CAS No.1206711-14-9
Purity>98%
FormulaC27H25N5O2
Mol Weight451.5197
ColorOff-white to yellow
StateSolid
SolubilityDMSO : 50 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20°C, 3 years , 4°C, 2 years; In solvent -20°C, 1 month.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Langenfeld J E, Langenfeld E. Src inhibition enhances BMP receptor antagonists downregulation of Id1 and growth suppression of lung cancer cells with a K-Ras mutation. 2013:5263.

[2]. Tsugawa D, Oya Y, Masuzaki R, et al. Specific activin receptor-like kinase 3 inhibitors enhance liver regeneration. J Pharmacol Exp Ther. 2014;351(3):549-558.

CoACoA of DMH2
Smiles:C1COCCN1CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3

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