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Product Information:

Dimethyl-SGD-1882

Dimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly potent DNA alkylator, and is used as an antibody-drug conjugate (ADC) cytotoxin. PBD Dimer is a DNA alkylator which inhibits DNA replication.

Cat. No.: EX-A13666    Purity: >98%
Chemical
Chemical structure of Dimethyl-SGD-1882


For research only, Do not use for Human!

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SynonymsDimethyl-PBD dimer
CAS No.3026416-27-0
Purity>98%
FormulaC44H43N5O7
Mol Weight753.8415
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Mantaj J, et al. From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody-Drug Conjugates (ADCs). Angew Chem Int Ed Engl. 2017 Jan 9;56(2):462-488.

CoACoA of Dimethyl-SGD-1882
Smiles:C[C@@]12N(C(C3=CC(OC)=C(OCCCOC4=C(C=C5C(N=C[C@]6(C)N(C=C(C7=CC=C(OC)C=C7)C6)C5=O)=C4)OC)C=C3N=C2)=O)C=C(C8=CC=C(N)C=C8)C1

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