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Product Information:

Difluoromethylornithine

Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.

Cat. No.: EX-A11311    Purity: >98%
Chemical
Chemical structure of Difluoromethylornithine


For research only, Do not use for Human!

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CAS No.70052-12-9
Purity>98%
FormulaC6H12F2N2O2
Mol Weight182.1685
ColorWhite to light yellow
Statesolid
SolubilityH2O : 83.33 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Burri C, et al. Eflornithine for the treatment of human African trypanosomiasis. Parasitol Res. 2003 Jun;90 Supp 1:S49-52.

[2]. Balfour JA, et al. Topical eflornithine. Am J Clin Dermatol. 2001;2(3):197-201; discussion 202.

[3]. Kumar A, et al. A method to improve the efficacy of topical eflornithine hydrochloride cream. Drug Deliv. 2016 Jun;23(5):1495-501.

[4]. Lipke DW, et al. Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. Clin Exp Hypertens. 1997 Apr;19(3):297-312.

CoACoA of Difluoromethylornithine
Smiles:C(CC(C(F)F)(C(=O)O)N)CN

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