Difluorinated Curcumin

Difluorinated Curcumin (3,4-Difluorobenzylidene curcumin) is a fluorinated curcumin analog with high bioavailability and anticancer activity. Difluorinated Curcumin inhibits the self-renewal ability of tumor stem/stem-like cells, clonogenicity, invasiveness and angiogenesis of tumor cells. Difluorinated Curcumin also increases cell sensitivity to chemotherapy.


Cat. No.: EX-A8908	Purity: >98%

	Chemical structure of Difluorinated Curcumin

For research only, Do not use for Human!

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Synonyms	3,4-Difluorobenzylidene curcumin
CAS No.	1170354-22-9
Purity	>98%
Formula	C28H22F2O6
Mol Weight	492.4675
Color	Light yellow to yellow
State	Solid
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Momtazi AA, et al. Difluorinated Curcumin: A Promising Curcumin Analogue with Improved Anti-Tumor Activity and Pharmacokinetic Profile. Curr Pharm Des. 2016;22(28):4386-97.
CoA	CoA of Difluorinated Curcumin

Smiles:	FC(C=C1/C=C(C(/C=C/C2=CC(OC)=C(C=C2)O)=O)/C(/C=C/C3=CC(OC)=C(C=C3)O)=O)=C(C=C1)F


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