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Product Information:

Deoxynivalenol

Deoxynivalenol, an orally active mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins (MRPs) inhibitors.

Cat. No.: EX-A5479    Purity: >98%
Chemical
Chemical structure of Deoxynivalenol


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg995In-stock
100mg1495In-stock
200mg2395In-stock
500mgget quote
1gget quote


CAS No.51481-10-8
Purity>98%
FormulaC15H20O6
Mol Weight296.3157
Color White to off-white
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL Ethanol 30 mg/mL
Shelf Life>2 years if stored properly
StoragePure -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Sergent T, et al. Deoxynivalenol transport across human intestinal Caco-2 cells and its effects on cellularmetabolism at realistic intestinal concentrations. Toxicol Lett. 2006 Jul 1;164(2):167-76.

[2]. Diesing AK, et al. Mycotoxin deoxynivalenol (DON) mediates biphasic cellular response in intestinal porcine epithelial cell lines IPEC-1 and IPEC-J2. Toxicol Lett. 2011 Jan 15;200(1-2):8-18.

[3]. Collins TF, et al. Effects of deoxynivalenol (DON, vomitoxin) on in utero development in rats. Food Chem Toxicol. 2006 Jun;44(6):747-57.

[4]. Forsell JH, et al. Comparison of acute toxicities of deoxynivalenol (vomitoxin) and 15-acetyldeoxynivalenol in the B6C3F1 mouse. Food Chem Toxicol. 1987 Feb;25(2):155-62.

[5]. Pestka JJ, et al. Immunochemical assessment of deoxynivalenol tissue distribution following oral exposure in the mouse. Toxicol Lett. 2008 May 5;178(2):83-7.

CoACoA of Deoxynivalenol

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