DDR1-IN-2

7rh (DDR1-IN-2) is a potent inhibitor of discoidin domain receptor 1 (DDR1), with an IC50 of 13.1 nM, and also less potently inhibits DDR2, with an IC50 of 203 nM. 7rh is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.


Cat. No.: EX-A14929	Purity: >98%

	Chemical structure of DDR1-IN-2

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	728	In-stock
500mg	1206	In-stock
1g	1900	In-stock
2g	3180	In-stock

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Synonyms	7rh
CAS No.	1429617-90-2
Purity	>98%
Formula	C30H29F3N6O
Mol Weight	546.5861
Color	White to light yellow
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 year;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Wang Z, et al. Tetrahydroisoquinoline-7-carboxamide Derivatives as New Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors. ACS Med Chem Lett. 2017 Feb 9;8(3):327-332.
CoA	CoA of DDR1-IN-2

Smiles:	O=C(NC1=CC(C(F)(F)F)=CC(CN2CCN(C)CC2)=C1)C3=CC=C(CC)C(C#CC4=CN5C(N=C4)=CC=N5)=C3


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