DDO-5936

DDO-5936 is a potent PPI inhibitor targeting Hsp90-Cdc37 protein-protein interaction (PPI) as Orally Active Inhibitors for the Treatment of Colorectal Cancer.


Cat. No.: EX-A5281	Purity: >98%

	Chemical structure of DDO-5936

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	650	In-stock
500mg	900	In-stock
1g	1650	In-stock
3g	3800	In-stock
5g	5900	In-stock
10g	5900	In-stock

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CAS No.	2355377-13-6
Purity	>98%
Formula	C25H29N5O4S
Mol Weight	495.594
Color	White to yellow
State	solid powder
Solubility	Soluble in DMSO 12.5 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Wang L, et al. Discovery and Optimization of Small Molecules Targeting the Protein-Protein Interaction of Heat Shock Protein 90 (Hsp90) and Cell Division Cycle 37 as Orally Active Inhibitors for the Treatment of Colorectal Cancer. J Med Chem. 2020 Feb 13;63(3):1281-1297. doi: 10.1021/acs.jmedchem.9b01659. [2]. Wang L, et al. Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer. Sci Adv. 2019 Sep 18;5(9):eaax2277. doi: 10.1126/sciadv.aax2277.
CoA	CoA of DDO-5936


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