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Product Information:

DBr-1

DBr-1 is a potent BRD9 PROTAC degrader (KD: 13 nM). DBr-1 can overcome intrinsic resistance to VHL-degrader.

Cat. No.: EX-A9177    Purity: >98%
Chemical
Chemical structure of DBr-1


For research only, Do not use for Human!

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Purity>98%
FormulaC55H68ClN9O5
Mol Weight970.639
 
 
Reference:  

[1]. Schröder M, et al. DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nat Commun. 2024 Jan 4;15(1):275.

CoACoA of DBr-1

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