DBCO-PEG3 acetic-EVCit-PAB

DBCO-PEG3 acetic-EVCit-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG3 acetic-EVCit-PAB is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.


Cat. No.: EX-A15718	Purity: >98%

	Chemical structure of DBCO-PEG3 acetic-EVCit-PAB

For research only, Do not use for Human!

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CAS No.	2253947-17-8
Purity	>98%
Formula	C54H72N8O13
Mol Weight	1041.1953
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
CoA	CoA of DBCO-PEG3 acetic-EVCit-PAB

Smiles:	C(CCC(NCCOCCOCCOCC(N[C@H](C(N[C@H](C(N[C@H](C(NC1=CC=C(CO)C=C1)=O)CCCNC(N)=O)=O)C(C)C)=O)CCC(OC(C)(C)C)=O)=O)=O)(=O)N2C=3C(C#CC=4C(C2)=CC=CC4)=CC=CC3


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