DBCO-β-Glu-PEG12-Exatecan

DBCO-β-Glu-PEG12-Exatecan (Compound 107) is an inhibitor for topoisomerase I. DBCO-β-Glu-PEG12-Exatecan can be used as a Drug-Linker Conjugate for ADC molecule .


Cat. No.: EX-A16835	Purity: >98%

	Chemical structure of DBCO-β-Glu-PEG12-Exatecan

For research only, Do not use for Human!

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CAS No.	3025107-83-6
Purity	>98%
Formula	C92H117FN8O30
Mol Weight	1833.9474
Color	Off-white to light yellow
State	Solid
Solubility	DMSO : 5 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture and light
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].BAJJURI K, et al., β-GLUCURONIDE LINKER-PAYLOADS, PROTEIN CONJUGATES THEREOF, AND METHODS THEREOF. WO2024006272.
CoA	CoA of DBCO-β-Glu-PEG12-Exatecan

Smiles:	N(C(OCC1=CC(CNC(CCNC([C@@H](NC(CCCCC(=O)N2C=3C(C#CC=4C(C2)=CC=CC4)=CC=CC3)=O)CNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)=O)=C(O[C@@H]5O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]5O)C=C1)=O)[C@@H]6C7=C8C(C=9N(C8)C(=O)C%10=C(C9)[C@](CC)(O)C(=O)OC%10)=NC=%11C7=


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