Inhibitor Specialist 
Product Information:
| Cat. No.: EX-A5673 | Purity: >98% |
 | |
| Chemical structure of Darexaban |
| Size | Unit Price (US$) | Stock | Quantity | Order |
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| Send PO to E-mail:[email protected]; or Fax:+86 020 81619670 |
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| Synonyms | YM-150 |
|---|---|
| CAS No. | 365462-23-3 |
| Purity | >98% |
| Formula | C27H30N4O4 |
| Mol Weight | 474.5515 |
| Color | Off-white to light yellow |
| State | solid powder |
| Solubility | Soluble in DMSO 250 mg/mL |
| Shelf Life | >2 years if stored properly |
| Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Reference: | [1]. Fukushi Hirayama, et al. Discovery of N-[2-hydroxy-6-(4-methoxybenzamido)phenyl]-4- (4-methyl-1,4-diazepan-1-yl)benzamide (darexaban, YM150) as a potent and orally available factor Xa inhibitor. J Med Chem. 2011 Dec 8;54(23):8051-65.
[2]. Seiji Kaku, et al. Darexaban: anticoagulant effects in mice and human plasma in vitro, antithrombotic effects in thrombosis and bleeding models in mice and effects of anti-inhibitor coagulant complex and recombinant factor VIIa. Thromb Res. 2013 May;131(5):450-6. [3]. Milan Remko, et al. Theoretical Study of Molecular Structure and Physicochemical Properties of Novel Factor Xa Inhibitors and Dual Factor Xa and Factor IIa Inhibitors. Molecules. 2016 Feb 4;21(2):185. |
| CoA | CoA of Darexaban |
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