Dansyl-NECA

Dansyl-NECA is a high affinity and selective fluorescent adenosine A1 receptor agonist (Ki values are 27, 3600 and 4300 nM for A1, A3 and A2 receptors, respectively). Permits visualization of A1 receptors in the rat cerebellar cortex.


Cat. No.: EX-A8516	Purity: >98%

	Chemical structure of Dansyl-NECA

For research only, Do not use for Human!

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Synonyms	Dansylhexyl NECA
CAS No.	219982-12-4
Purity	>98%
Formula	C30H40N8O6S
Mol Weight	640.754
State	solid powder
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Macchia M, Salvetti F, Barontini S, et al. Fluorescent probes for adenosine receptors: synthesis and biology of N6-dansylaminoalkyl-substituted NECA derivatives. Bioorg Med Chem Lett. 1998;8(22):3223-3228. doi:10.1016/s0960-894x(98)00582-4 [2]. Kozma E, Jayasekara PS, Squarcialupi L, et al. Fluorescent ligands for adenosine receptors. Bioorg Med Chem Lett. 2013;23(1):26-36. doi:10.1016/j.bmcl.2012.10.112
CoA	CoA of Dansyl-NECA

Smiles:	CN(C)C1=C2C(C(S(NCCCCCCNC3=NC=NC4=C3N=CN4[C@H]5[C@H](O)[C@H](O)[C@@H]([C@@](NCC)=O)O5)(=O)=O)=CC=C2)=CC=C1


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