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Product Information:

Danicamtiv

Danicamtiv is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.

Cat. No.: EX-A5015    Purity: >98%
Chemical
Chemical structure of Danicamtiv


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg550In-stock
25mg950In-stock
50mg1450In-stock
100mg2200In-stock
200mg3500Inquire


CAS No.1970972-74-7
Purity>98%
FormulaC16H20F3N5O4S
Mol Weight435.421
ColorOff-white to light yellow
Statesolid powder
SolubilitySoluble in DMSO 50 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Sarah Fernandes, et al. Abstract 15707: MYK-491, a Novel Small-Molecule Cardiac Myosin Activator Increases Cardiac Systolic Function and Preserves Mechanical Efficiency: Pre-Clinical in vivo and in vitro Evidence. Circulation. 2019;140:A15707

[2]. Voors AA, et al. Effects of danicamtiv, a novel cardiac myosin activator, in heart failure with reduced ejection fraction: experimental data and clinical results from a phase 2a trial. Eur J Heart Fail. 2020;22(9):1649-1658.

CoACoA of Danicamtiv

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