Dalvotoclax

Dalvotoclax (Example 8) is a selective inhibitor of BCL-2. Dalvotoclax has good liver microsomal stability. Dalvotoclax inhibits the activity of anti-apoptotic BCL-2 protein and anti-apoptotic BCL-XL protein. Dalvotoclax can be studied in research for B cell leukemia.


Cat. No.: EX-A13639	Purity: >98%

	Chemical structure of Dalvotoclax

For research only, Do not use for Human!

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CAS No.	2416927-21-2
Purity	>98%
Formula	C45H47ClF3N7O8S
Mol Weight	938.41
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Fei Liu, et al., Trifluoromethyl-substituted sulfonamide as bcl-2-selective inhibitor. WO2020088442A1.
CoA	CoA of Dalvotoclax

Smiles:	O=C(C(C=CC(N1CCN(CC(CCC(C)(C2)C)=C2C3=C(Cl)C=C(C(F)(F)F)C=C3)CC1)=C4)=C4OC5=CN=C6NC=CC6=C5)NS(C7=CC([N+]([O-])=O)=C(NC[C@H]8COCCO8)C=C7)(=O)=O


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