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Product Information:

D8-MMAE

D8-MMAE is a deuterated labeled MMAE, a potent mitotic inhibitor and a tubulin inhibitor.

Cat. No.: EX-A4341    Purity: >98%
Chemical
Chemical structure of D8-MMAE


For research only, Do not use for Human!

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SynonymsD8-Monomethyl auristatin E
CAS No.2070009-72-0
Purity>98%
FormulaC39H67N5O7
Mol Weight726.0279
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Li F, et al. Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models. Cancer Res. 2016 May 1;76(9):2710-9.

CoACoA of D8-MMAE
Smiles:CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@@](C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])([2H])NC([C@H](C(C)C)NC)=O)=O)C

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