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Product Information:

CYM50358

CYM50358 is a potent, selective antagonist of the sphingosine-1-phosphate receptor 4 (S1P4). CYM50358 inhibits S1P4 with an IC50 of 25 nM.

Cat. No.: EX-A5683    Purity: >98%
Chemical
Chemical structure of CYM50358


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg685In-stock
100mg985In-stock
200mg1485In-stock


CAS No.1314212-39-9
Purity>98%
FormulaC20H18Cl2N2O2
Mol Weight389.275
ColorOff-white to yellow
Statesolid powder
SolubilitySoluble in DMSO 125 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Guerrero, Miguel et al. Discovery, design and synthesis of the first reported potent and selective sphingosine-1-phosphate 4 (S1P4) receptor antagonists. Bioorganic & medicinal chemistry letters vol. 21,12 (2011): 3632-6.

[2]. Onuma, Takashi et al. Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. Thrombosis research vol. 156 (2017): 91-100.

CoACoA of CYM50358

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