CYCLO-(PHE-ARG-GLY-ASP-LEU-ALA-PHE-D-PRO-(NME)LYS)

Cyclic αvβ6 (Compound c(FRGDLAFp(NMe)K)) is a αvβ6-integrin-specific cyclic nonapeptide. Cyclic αvβ6 can be coupled with 68Ga-labeled monomeric triazacyclononane-triphosphinate (TRAP). Cyclic αvβ6 can be used in PET imaging studies for cancers including head and neck cancer and pancreatic cancer.


Cat. No.: EX-A11298	Purity: >98%

	Chemical structure of CYCLO-(PHE-ARG-GLY-ASP-LEU-ALA-PHE-D-PRO-(NME)LYS)

For research only, Do not use for Human!

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CAS No.	2089299-82-9
Purity	>98%
Formula	C51H75N13O11
Mol Weight	1046.2217
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Quigley NG, et al. PET/CT imaging of head-and-neck and pancreatic cancer in humans by targeting the "Cancer Integrin" αvβ6 with Ga-68-Trivehexin. Eur J Nucl Med Mol Imaging. 2022 Mar;49(4):1136-1147.
CoA	CoA of CYCLO-(PHE-ARG-GLY-ASP-LEU-ALA-PHE-D-PRO-(NME)LYS)

Smiles:	O=C1N2[C@@](C(=O)N(C)[C@@H](CCCCN)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H]1CC4=CC=CC=C4)(CCC2)[H]


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