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Product Information:

CX-5011

CX-5011 is a CK2 inhibitor. CX-5011 also induces Rac1 activation. CX-5011 induces apoptosis and induces cancer cell death .

Cat. No.: EX-A9375    Purity: >98%
Chemical
Chemical structure of CX-5011


For research only, Do not use for Human!

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CAS No.1333382-30-1
Purity>98%
FormulaC20H11N4NaO2
Mol Weight362.3167
Coloryellow
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. D'Amore C, et al. "Janus" efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms. Biochim Biophys Acta Mol Cell Res. 2020 Nov;1867(11):118807.

[2]. Salizzato V, et al. Inhibition of protein kinase CK2 by CX-5011 counteracts imatinib-resistance preventing rpS6 phosphorylation in chronic myeloid leukaemia cells: new combined therapeutic strategies. Oncotarget. 2016 Apr 5;7(14):18204-18.

CoACoA of CX-5011
Smiles:O=C(C1=CC=C2C3=CN=CN=C3C(NC4=CC=CC(C#C)=C4)=NC2=C1)O[Na]

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