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Product Information:

CWP232228

CWP232228, a highly potent selective Wnt/β-catenin signaling inhibitor, antagonizes binding of β-catenin to T-cell factor (TCF) in the nucleus.

Cat. No.: EX-A4797    Purity: 98+%
Chemical
Chemical structure of CWP232228


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg685In-stock
25mg985In-stock
50mg1385In-stock
100mg1985In-stock
200mg2785In-stock
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SynonymsCWP-232228
Synonyms 2CWP232228 sodium
CAS No.1144044-02-9
Purity98+%
FormulaC33H34N7Na2O7P
Mol Weight717.6191
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Jang GB, et al. Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells. Cancer Res. 2015 Apr 15;75(8):1691-702.

[2]. Kim JY, et al. Oncotarget. 2016 Apr 12;7(15):20395-409. CWP232228 targets liver cancer stem cells through Wnt/β-catenin signaling: a novel therapeutic approach for liver cancer treatment.

CoACoA of CWP232228
Smiles:CN1C=C2C=CC=C(C2=N1)CN3C[C@H]4N([C@H](C3=O)CC5=CC=C(C=C5)OP(=O)([O-])[O-])C(=O)CN(N4C(=O)NCC6=CC=CC=C6)CC=C.[Na+].[Na+]

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