CWI1-2

CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects .


Cat. No.: EX-A7989	Purity: >98%

	Chemical structure of CWI1-2

For research only, Do not use for Human!

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CAS No.	2408590-36-1
Purity	>98%
Formula	C22H17Cl3N6O3
Mol Weight	519.768
Color	Light yellow to yellow
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Hengyou Weng, et al. The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia. Cancer Cell. 2022 Dec 12;40(12):1566-1582.e10.
CoA	CoA of CWI1-2

Smiles:	OC(C=C1)=C(C=C1Cl)/C=N/N=C(N/N=C\C(C=C2Cl)=C(C=C2)O)\N/N=C/C(C=C3Cl)=C(C=C3)O


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