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Product Information:

CSLP37

CSLP37 is a selective RIPK2 inhibitor with an IC50 of 16.3 nM. CSLP37 shows no inhibitory activity against RIPK1 and RIPK3. CSLP37 displays potent suppression of cellular NOD1 and NOD2 responses.

Cat. No.: EX-A11279    Purity: >98%
Chemical
Chemical structure of CSLP37


For research only, Do not use for Human!

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SynonymsCSLP 37
CAS No.2244984-64-1
Purity>98%
FormulaC25H30FN5O3S
Mol Weight499.601
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Matous Hrdinka, et al. Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling. EMBO J. 2018 Sep 3;37(17):e99372.

CoACoA of CSLP37
Smiles:O=S(=O)(NC=1C=C(C=C(F)C1OC)C2=CC(=CN=C2N)C=3C=CC(=CC3)N4CCNCC4)CCC

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