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Product Information:

CSF1R-IN-20

CSF1R-IN-20 (compound 7a) is a CSF-1R Inhibitor with an IC50 value of 467 nM. CSF1R-IN-20 inhibits CSF-1R auto-phosphorylation .

Cat. No.: EX-A9043    Purity: >98%
Chemical
Chemical structure of CSF1R-IN-20


For research only, Do not use for Human!

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CAS No.2935479-57-3
Purity>98%
FormulaC25H26F3N5O3
Mol Weight501.5008
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Jihyun Baek, et al. Discovery of N-(5-amido-2-methylphenyl)-5-methylisoxazole-3-carboxamide as dual CSF-1R/c-Kit Inhibitors with improved stability and BBB permeability. Eur J Med Chem. 2024 Feb 20:268:116253.

CoACoA of CSF1R-IN-20
Smiles:O=C(NC1=CC(=CC=C1C)NC(=O)C=2C=C(C=C(C2)C(F)(F)F)N3CCN(C)CC3)C4=NOC(=C4)C

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