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Product Information:

crozbaciclib

Crozbaciclib (CDK4/6/1 Inhibitor) is a CDK4/6 inhibitor with IC50s of 3 and 1 nM, respectively.

Cat. No.: EX-A10194    Purity: >98%
Chemical
Chemical structure of crozbaciclib


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
1mg305In-stock
5mg560In-stock
10mg850In-stock
25mg1680In-stock
50mg2800In-stock
100mg4500In-stock


SynonymsCDK4/6/1 Inhibitor
CAS No.2099128-41-1
Purity>98%
FormulaC28H30F2N6
Mol Weight488.5748
Coloroff-white to yellow
Statesolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Yin L, et al. A highly potent CDK4/6 inhibitor was rationally designed to overcome blood brain barrier in gliobastoma therapy. Eur J Med Chem. 2018 Jan 20;144:1-28.

CoACoA of crozbaciclib
Smiles:CC(C1(CCCC1)C2=CC(C3=NC(NC4=CC=C(C5CCN(C)CC5)C=N4)=NC=C3F)=C6)=NC2=C6F

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