cRIPGBM

cRIPGBM, a proapoptotic derivative of RIPGBM, a cell type-selective inducer of apoptosis in GBM cancer stem cells (CSCs) by binding to receptor-interacting protein kinase 2 (RIPK2), with an EC50 of 68 nM in GBM-1 cells.


Cat. No.: EX-A5212	Purity: >98%

	Chemical structure of cRIPGBM

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
10mg	950	Inquire
50mg	1850	Inquire

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CAS No.	2361988-77-2
Purity	>98%
Formula	C26H20ClFN2O2
Mol Weight	446.901
Color	Light yellow to yellow
State	solid powder
Solubility	Soluble in DMSO 25 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Lucki NC, et al. A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6435-6440.
CoA	CoA of cRIPGBM

Smiles:	O=C1C2=C([N+](CC3=CC=C(F)C=C3)=C(C)N2CC4=CC=CC=C4)C(C5=C1C=CC=C5)=O.[Cl-]


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