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Product Information:

CPPG

CPPG ((RS)-CPPG) is a potent group II/III mGlu receptors antagonist. CPPG exhibits some selectivity (approximately 20 fold) for group III (IC50=2.2 nM) over group II (IC50=46.2 nM) mGlu receptors in the rat cerebral cortex. CPPG has weak effects at group I mGlu receptors[1].

Cat. No.: EX-A14459    Purity: >98%
Chemical
Chemical structure of CPPG


For research only, Do not use for Human!

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Synonyms(RS)-CPPG
CAS No.183364-82-1
Purity>98%
FormulaC11H14NO5P
Mol Weight271.2063
ColorWhite to off-white
StateSolid
Solubilitysoluble in NaOH
Shelf Life>3 years if stored properly
StoragePowder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Toms NJ, et al. The effects of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist. Br J Pharmacol. 1996 Nov;119(5):851-4.

CoACoA of CPPG
Smiles:C1CC1C(C2=CC=C(C=C2)P(=O)(O)O)(C(=O)O)N

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