CP-775146

CP-775146 is a selective PPARα agonist (Ki of 24.5 nM) that binds strongly to the PPARα ligand. CP-775146 has no observable affinity for PPARβ and PPARγ.CP-775146 shows hypolipidemic activity. CP-775146 efficiently alleviates obesity-induced liver damage, prevents lipid accumulation by activating the liver fatty acid β-oxidation pathway .


Cat. No.: EX-A10867	Purity: >98%

	Chemical structure of CP-775146

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	500	In-stock
100mg	800	In-stock
250mg	1250	In-stock
500mg	2000	In-stock
1g	3200	In-stock

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CAS No.	702680-17-9
Purity	>98%
Formula	C26H33NO4
Mol Weight	423.5445
Color	white to off-white
State	solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, sealed storage, away from moisture and light, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Kane CD, et al. Molecular characterization of novel and selective peroxisome proliferator-activated receptor alpha agonists with robust hypolipidemic activity in vivo. Mol Pharmacol. 2009 Feb;75(2):296-306. [2]. Shengjie Tang, et al. The Effects of New Selective PPAR α Agonist CP775146 on Systematic Lipid Metabolism in Obese Mice and Its Potential Mechanism. J Diabetes Res. 2020 May 4;2020:4179852.
CoA	CoA of CP-775146

Smiles:	CC(OC1=CC=CC([C@H]2CN(C(CC3=CC=C(C(C)C)C=C3)=O)CCC2)=C1)(C)C(O)=O


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