COX-2/15-LOX-IN-5

COX-2/15-LOX-IN-5 (Compound 4f) is a dual inhibitor of COX-2/15-LOX. COX-2/15-LOX-IN-5 attenuates increased NF-κB activation in RAW 264.7 macrophages mediated by lipopolysaccharide. COX-2/15-LOX-IN-5 has anti-inflammatory and antioxidant activities.


Cat. No.: EX-A13492	Purity: >98%

	Chemical structure of COX-2/15-LOX-IN-5

For research only, Do not use for Human!

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CAS No.	443790-30-5
Purity	>98%
Formula	C25H21N3O3S
Mol Weight	443.518
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Osman NA, et al. Dual COX-2 and 15-LOX inhibition study of novel 4-arylidine-2-mercapto-1-phenyl-1H-imidazolidin-5(4H)-ones: Design, synthesis, docking, and anti-inflammatory activity. Arch Pharm (Weinheim). 2024 Feb 5:e2300615.
CoA	CoA of COX-2/15-LOX-IN-5

Smiles:	O=C1C(N=C(SCC(=O)NC2=CC=C(OC)C=C2)N1C=3C=CC=CC3)=CC=4C=CC=CC4


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