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Product Information:

COX-2/15-LOX-IN-2

COX-2/15-LOX-IN-2 is a potent dual COX-2 and 15-LOX inhibitor with IC50 values of 0.065 μM and 1.86 μM, respectively. COX-2/15-LOX-IN-2 has potent antioxidant activity.

Cat. No.: EX-A13490    Purity: >98%
Chemical
Chemical structure of COX-2/15-LOX-IN-2


For research only, Do not use for Human!

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100mgget quote
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CAS No.3052736-49-6
Purity>98%
FormulaC27H26N6OS2
Mol Weight514.665
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Sara Elsayed, et al. Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors endowed with potent antioxidant activity . Eur J Med Chem. 2023 Nov 15;260:115724.

CoACoA of COX-2/15-LOX-IN-2
Smiles:N=1C=NC(NNC=2N=C(N=C3SC4=C(C32)CCCC4)C=5C=CC(OC)=CC5)=C6C1SC7=C6CCCC7

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