Copper probe CF4

Copper Fluor-4 (CF4) is a Cu +-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 has high copper selectivity with a Kd value of 2.9×10 −13 M, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 is stable in a physiologically relevant pH regime between 6 and 8 (wavelengths of 415 nm for excitation and 660 nm for emission) .


Cat. No.: EX-A15610	Purity: >98%

	Chemical structure of Copper probe CF4

For research only, Do not use for Human!

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250mg	3482	Inquire
500mg	4976	Inquire

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Synonyms	CF4
Synonyms 2	Copper Fluor-4
CAS No.	2365532-64-3
Purity	>98%
Formula	C38H47F3N2O2S4
Mol Weight	749.047
Color	Brown to reddish brown
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, protect from light; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Xiao T, et al. Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system. Nat Chem Biol. 2018 Jul;14(7):655-663. [2]. Weishaupt AK, et al. Dysfunction in atox-1 and ceruloplasmin alters labile Cu levels and consequently Cu homeostasis in C. elegans. Front Mol Biosci. 2024 Feb 8;11:1354627. [3]. Chakraborty K, et al. Copper dependent ERK1/2 phosphorylation is essential for the viability of neurons and not glia. Metallomics. 2022 Apr 1;14(4):mfac005.
CoA	CoA of Copper probe CF4

Smiles:	O=C1C=CC=2C(OC=3C=C(C=CC3C2C=4C=CC(=CC4C(F)(F)F)CN(CCSCCSCC)CCSCCSCC)N5CCCCC5)=C1


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