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Product Information:

Contezolid

Contezolid (MRX-I), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid (MRX-I) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI).

Cat. No.: EX-A7015    Purity: >98%
Chemical
Chemical structure of Contezolid


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg850In-stock
500mg1300In-stock
1g2400In-stock


SynonymsMRX-I
CAS No.1112968-42-9
Purity>98%
FormulaC18H15F3N4O4
Mol Weight408.3313
Color White to light yellow
Statesolid powder
SolubilitySoluble in DMSO 120 mg/mL
Shelf Life>2 years if stored properly
StoragePowder 4℃, sealed storage, away from moisture and light In solvent : -80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture and light)
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Junzhen Wu, et al. Evaluation of the Effect of Contezolid (MRX-I) on the Corrected QT Interval in a Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study in Healthy Chinese Volunteers. Antimicrob Agents Chemother. 2020 May 21;64(6):e02158-19.

[2]. Mikhail F Gordeev, et al. New potent antibacterial oxazolidinone (MRX-I) with an improved class safety profile. J Med Chem. 2014 Jun 12;57(11):4487-97.

[3]. Carolyn Shoen, et al. In Vitro and In Vivo Activities of Contezolid (MRX-I) against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00493-18.

CoACoA of Contezolid

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