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Product Information:

Cobicistat

Cobicistat is a potent and selective inhibitor of cytochrome P450 3A (CYP3A) enzymes with IC50s of 30-285 nM.

Cat. No.: EX-A2578    Purity: >98%
Chemical
Chemical structure of Cobicistat


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg350In-stock
250mg550In-stock
500mg850In-stock
1g1200In-stock
5g3850In-stock
10g6160In-stock


SynonymsGS-9350
CAS No.1004316-88-4
Purity>98%
FormulaC40H53N7O5S2
Mol Weight776.023
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lianhong Xu, et al. Cobicistat (GS-9350): A Potent and Selective Inhibitor of Human CYP3A as a Novel Pharmacoenhancer. ACS Med. Chem. Lett., 2010, 1 (5), pp 209–213

[2]. Temesgen Z. Cobicistat, a pharmacoenhancer for HIV treatments. Drugs Today (Barc). 2013 Apr;49(4):233-7.

CoACoA of Cobicistat
Smiles:CC(C)C1=NC(CN(C)C(=O)N[C@@H](CCN2CCOCC2)C(=O)N[C@H](CC[C@H](CC2=CC=CC=C2)NC(=O)OCC2=CN=CS2)CC2=CC=CC=C2)=CS1

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